Posts

The Effect of Ketogenic Diets on Thyroid Hormones

The previous generation of myths about low carb diets were focused on organ systems. They warned of things like kidney dysfunction, and osteoporosis. As these myths became untenable, new myths have swiftly taken their place: myths, for example, about hormone systems, and gut bacteria.In previous posts, such as here, and here, we dispelled misinformation arising […]

Keto-adapted, but no ketones?

One of the cheapest and easiest ways to measure ketones is to use ketone test strips, e.g. Ketostix. Ketone test strips use a chemical reaction to measure acetoacetate (see below), usually in urine, though the same method can be used for blood. (Not to be confused with the blood strips used at home for beta-hydroxybutyrate.) […]

The Ketogenic Diet’s Effect on Cortisol Metabolism

(Related post: Red Light, Green Light: responses to cortisol levels in keto vs. longevity research) One of the myths surrounding ketogenic diets comes from misunderstanding the role of cortisol — the “stress hormone”. In a previous post, we addressed one of the arguments behind this myth: the idea that to activate gluconeogenesis (to make glucose […]

Science Fiction

We humans are storytellers. When we want something to be memorable and meaningful, we make it into a story that can be interpreted causally. Our brains are just made that way [1], [2]. That may be why adding dramatic anecdotes to a book or article can make it more popular and persuasive than sticking solely […]

Babies thrive under a ketogenic metabolism

Some people, even some scientists who study ketogenic metabolism, have the idea that ketogenesis is somehow abnormal, or exceptional; an adaptation for emergencies only. We disagree. One reason we think a ketogenic metabolism is normal and desirable, is that human newborns are in ketosis. Despite the moderate sugar content of human breast milk, breastfeeding is […]

Language Barriers: Preferred Fuel

by Amber Wilcox-O’Hearn As a linguist, I am often struck by the way phrasing and word choices not only reflect biases, but can actually create them [1]. Again and again in my researches into dietary science, I come upon expressions and turns of phrase that make Low Carb, High Fat diets seem intuitively unhealthy or […]

How much protein is enough?

It seems, from clinical claims and numerous anecdotes, that protein intake has to be below some threshold for ketogenesis to continue, all else being equal. (Conditions are rarely equal: the effects of fat intake, calorie intake, the profile of amino acids in your diet, the type of fat in your diet, exercise, and frequency of […]

Similarities between germ-free mice and ketogenic humans

Tracing a chain of ideas Sometimes the assumptions that scientists start with about what is “good”, “healthy”, or “normal” can cause them to interpret results in a completely different way than someone starting with different assumptions would have. Then, the resulting conclusions become the assumptions in the next round of interpretation, leading to a chain […]

The Ketogenic Diet Reverses Indicators of Heart Disease

Cardiovascular disease (CVD) is the leading cause of death worldwide 1. Because of its prevalence and life-threatening nature, and because it appears that a keto diet is likely to reverse it, we consider it one of the most important conditions to discuss here. In our last post, we argued that CVD, being a disease strongly […]

The Ketogenic Diet as a Treatment for Metabolic Syndrome

Metabolic Syndrome (MetS) can be viewed as a set of symptoms of insulin resistance. Taken together, those symptoms signify a threat of heart disease, diabetes, cancer, and other diseases that appear to be different manifestations of a common cause. That common cause is likely to be insulin resistance. This hypothesis is supported by evidence that […]