Posts

Protein, Gluconeogenesis, and Blood Sugar

Recently (for some conception of recent) we asked the question: If You Eat Excess Protein, Does It Turn Into Excess Glucose? One of the potentially confusing aspects of this question, is the difference between gluconeogenesis (GNG) — the creation of new glucose that didn’t exist before, and increases in blood sugar. In response to our […]

We were talking about gluconeogenesis, not ketogenesis.

Our last post described the evidence that the rate of gluconeogenesis (GNG) is stable under a variety of metabolic conditions. We also described several experiments in which large amounts of protein were ingested or infused and did not increase the rate. We concluded that eating more protein than your body needs probably doesn’t increase GNG. […]

If You Eat Excess Protein, Does It Turn Into Excess Glucose?

Gluconeogenesis is Demand-Driven, not Supply-Driven We have seen the claim that any protein you eat in excess of your immediate needs will be turned into glucose by spontaneous gluconeogenesis 1. (Gluconeogenesis (GNG) is the process by which glucose is made out of protein in the liver and kidneys.) Some people think that because protein can be […]

Ketogenic Diets, Cortisol, and Stress: Part I — Gluconeogenesis

One recent myth, prevalent in the Paleo Diet community, is that the keto diet is stressful to the body1. This idea arises from misunderstandings about cortisol — “the stress hormone”. There are two different arguments we know of, and this post will address the first one, the “gluconeogenesis requires cortisol” myth. This myth comes from […]